Arsenal, who had 23 shots to Newcastle's seven, piled on the pressure late on to try to reduce the deficit but Newcastle manned the barricades to take a healthy lead to St James' Park.
Inspirational manager Juergen Klopp has rekindled the Anfield flame though and delivered the club's 19th top-flight title, one behind arch-rivals United's record of 20, after finishing runners-up to City in a thrilling race last season.
Manchester City manager Pep Guardiola accused Sadio Mane of diving after the Liverpool forward's match-winning display against Aston Villa in the English Premier League.
Liverpool's 30-year wait for their 19th English top-flight crown ended on Thursday when Manchester City lost at Chelsea and thousands of fans turned up at Anfield to celebrate.
Liverpool forward Sadio Mane has become the second player from the English Premier League champions to test positive for COVID-19 this week.
A first-half penalty earned Lille a shock 1-0 home victory over holders Real Madrid in the Champions League group phase on Wednesday.
Images from Saturday's action in the Premier League.
A summary of Saturday's action in the Serie A, Ligue 1 and Bundesliga
Liverpool stayed in the hunt for a top-four Premier League finish with a 1-0 win at Wolverhampton Wanderers
A round-up of the UEFA Champions League last-16 first leg matches played on Tuesday.
Tracking the key moves this week in the European transfer market
Tottenham Hotspur and Liverpool raised the spirits with a rip-roaring 2-2 draw in a pre-Christmas Premier League classic on Sunday after a weekend marred by COVID-19 related postponements.
Leandro Trossard transformed the mood at Arsenal with the winning goal as they recovered from an early setback to beat Tottenham Hotspur 2-1 at home.
Twelve months ago Liverpool were ripping up the record books on the way to their first English top-flight title for 30 years but defeat by Everton on Saturday left them mulling a host of far less flattering statistics.
The fixture was originally scheduled to be played on May 3 but was postponed after violent clashes between fans and police in which more than 100 supporters forced their way into the stadium and stormed the pitch to protest against the club's owners -- the Glazer family.
Roberto Firmino scored twice as Liverpool boosted their hopes of Champions League football next season
A summary of Saturday's action in the English Premier League.
Liverpool continued their relentless march to a first English title in 30 years, easing to a 2-0 victory at West Ham United on Wednesday to move 19 points clear at the Premier League summit. Mohamed Salah fired them ahead from the penalty spot in the first half and Alex Oxlade-Chamberlain doubled their advantage early in the second to wrap up a remarkable 23rd win from 24 games this season and stretch their unbeaten league run to 40.
Mohamed Salah hit a hat-trick as Liverpool humiliated Manchester United, romping to a stunning 5-0 victory at Old Trafford in the Premier League on Sunday that leaves Ole Gunnar Solskjaer's future in serious doubt.
Champions Manchester City could only muster a 2-2 Premier League draw with Brighton & Hove Albion on Saturday.
Images from Premier League matches played on Wednesday.
Liverpool's 30-year wait for their 19th English top-flight title ended on Thursday after second-placed Manchester City were beaten by Chelsea, giving Juergen Klopp's side an unassailable 23-point lead with seven games left.
Liverpool's Slot not nervous ahead of Anfield debut
His mother Elisabeth had passed away last month.
Alexander Isak's early headed goal lifted Newcastle to a 1-0 victory over Arsenal on Saturday at St. James' Park, as Eddie Howe's men delivered a blow to Arsenal's title chase with their first win in six Premier League outings.
Images from the English Premier League matches played on Wednesday night.
first English title for 30 years had been sealed almost a month ago with seven games remaining, following a three-month stoppage because of the COVID-19 pandemic.
Liverpool's defence of a Premier League crown won at a canter last season has become a nightmare
Goalkeeper Alisson Becker scored a stunning header in the fifth minute of stoppage-time as Liverpool snatched a 2-1 victory at the death against relegated West Bromwich Albion at The Hawthorns on Sunday.
Chelsea moved into the Premier League's top four as Mason Mount's superb first-half goal earned them a 1-0 win at champions Liverpool who suffered a club-record fifth straight home league defeat on Thursday.
Liverpool raised the bar so high and enjoyed such a huge winning margin in claiming the English Premier League title last season it would be churlish to doubt their credentials for a repeat showing.
Liverpool will resume their quest for a first top-flight title in 30 years against Everton on June 21 but the venue for the behind-closed-doors fixture was not confirmed when the league released its revised fixtures for the season's restart.
IMAGES from the English Premier League matches played on Sunday.
Champions Liverpool are five points clear at the top of the Premier League after a 7-0 away hammering of Crystal Palace while Arsenal's troubles continued with a 2-1 defeat at second-placed Everton on Saturday.
A round-up of Sunday's action in the Premier League.
Chelsea kept alive their remote Premier League title chances with a 2-0 win over London rivals Tottenham Hotspur on Sunday, set on their way by an exquisite strike from Hakim Ziyech which was quickly followed up by a Thiago Silva header.
Postecoglou moves a step closer to making good on his reputation for securing silverware in his second season at clubs and delivering a first cup for Spurs since they won the League Cup in 2008.
Manchester City came from behind twice to earn a 2-2 draw with Liverpool in a breathless and pulsating Premier League encounter, at Anfield, on Sunday. All four goals came in the second half.
This was not quite Liverpool back to their best but it was an important statement of intent for Klopp's side that they will not be giving up their title without a fight.
Ronaldo back for Man Utd but injured Shaw faces weeks out
